Regenerx Biopharmaceuticals, Inc. It ‘s been reported that serum thymosin 4 levels were significantly lower in patients with chronic hepatitis B and the magnitude of the reduction of thymosin 4 was closely related to the severity of liver disease and the patient’s death. Because patients with higher levels of T 4 survived the illness, changes in the values of T 4 may reflect the results in some patients with renal impairment.The research team was led by Tao Han, MD, Ph.D., Professor, Department of Hepatology, Tianjin Institute of Hepatobiliary Diseases, Tianjin Medical University, Tianjin, China. The document has been published in World Journal of Gastroenterology, February 7, 2010, Volume 16, Issue 5, pp
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Liver failure occurs when the extension of the hepatocytes death exceeds the regenerative capacity of the liver, and recent discoveries have shown that T 4 regulates certain molecules that play a role in preventing cell death and promote liver regeneration liver. Regeneration of the liver is considered to be deleted in liver failure.
‘The study showed that the level of thymosin 4 was significantly reduced in patients with renal impairment, suggesting that thymosin 4 could become a new therapeutic agent for liver failure caused by chronic HBV infection,’ said the team has concluded of research.